Imaging for Chronic Sinusitis

Do you have a patient with "chronic sinusitis" and you want to order some imaging?

• Order a limited CT scan of sinuses (without contrast)
• This costs about the same as a sinus x-ray
• But it gives way better images!

Testing for Celiac Disease (Celiac Sprue)

Here are some tips regarding Celiac Disease:

• All patients with history of "irritable bowel syndrome" should be tested for celiac disease
• Testing should be done on a HIGH gluten diet
• These test have the highest diagnostic accuracy (better than IgG):
• Endomysial IgA 
• Tissue transglutaminase IgA 
• Diagnosis needs to be confirmed with small bowel biopsy

REVISIT: Glycohemaglobin and Average Plasma Glucose

In a previous post, we discussed a quick tip to calculate the A1C, here is an EVEN QUICKER tip provided by Dr. Eddie Needham (in which Dr. Carlos Dumois started the entire discussion):

Ave Glucose = (A1C — 2) x 30

So a patient with an A1C of 10 would have an average glucose = (10 — 2) x 30. Or 240. Simple awesomeness. 

Testing for HSV

This tip is from one of our esteemed residents Dr. Jennifer Stuart:

According to UpToDate, to diagnose an acute herpes infection, viral culture on an unroofed lesion is only about 50% sensitive in diagnosing HSV. A much better (and expensive) test is to order the

HSV PCR 

of the mucosal specimen. The HSV PCR is especially helpful in detecting asymptomatic HSV shedding.

So where does serology fit in? To be honest, I'm not sure. I don't check HSC IgG since I  don't typically care about testing for an previous infection (which may not reoccur). Testing for HSV IgM may be helpful, but in the setting of a very early initial or reactivated infection, it may be falsely negative. 

Testing for Mononucleosis

In day to day practice, I order a monospot to screen for mono. But sometimes, the monospot can give a false negative reading (especially early in the disease). For those times where I need something more sensitive (and more expensive), I will order this:

EBV VCA IgM

Which affectionately stands for Epstein-Barr Virus, Virus Capsid Antigen IgM.

Urine Drug Screens

BEFORE ordering a urine drug screen, make sure to ask when your patient last took EVERY controlled medication that you prescribe. And document that conversation in the chart. It is impossible to interpret the drug screen if we don't know what to expect.